Pivalic Acid

• CAT Number: R042088
• CAS Number: 75-98-9
• Molecular Formula: C5H10O2
• Molecular Weight: 102.13
• Purity: ≥95%
• Synonyms: 2,2-Dimethylpropanoic Acid; 2,2,2-Trimethylacetic Acid; 2,2-Dimethylpropanoic Acid; 2,2-Dimethylpropionic Acid; NSC 65449; Neopentanoic Acid; Neovaleric Acid; Trimethylacetic Acid; Trimethylmethanecarboxylic Acid; Versatic 5 Acid; tert-Pentanoic Acid
• Storage: -20°C
• IUPAC Name: 2,2-dimethylpropanoic acid
• InChI: InChI=1S/C5H10O2/c1-5(2,3)4(6)7/h1-3H3,(H,6,7)
• InChIKey: IUGYQRQAERSCNH-UHFFFAOYSA-N
• SMILES: CC(C)(C)C(=O)O

Pivalic acid (CAT: R042088) is a highly branched, aliphatic carboxylic acid characterized by a tert-butyl group adjacent to the carboxyl function. This crystalline solid is widely used in organic synthesis as a sterically hindered acid, particularly valuable for forming pivaloyl-protected intermediates that resist hydrolysis and oxidation. It serves as a building block in pharmaceuticals, agrochemicals, and polymer chemistry. Pivalic acid is also used in esterification reactions and as a reference compound in acidity studies. Its bulky structure imparts stability to derivatives, making it ideal for protecting groups and modifying reactivity in complex synthetic pathways.