Pirenzepine, Dihydrochloride

• CAT Number: R004749
• CAS Number: 29868-97-1
• Molecular Formula: C19H21N5O2.2HCl
• Molecular Weight: 424.33
• Purity: ≥95%
• Synonyms: 5,11-Dihydro-11-[2-(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzo-?diazepin-6-one Dihydrochloride; Duogastral; Durapirenz; Gasteril; Gastrozepin; Leblon; Maghen; Renzepin; Tabe; Ulcuforton; Ulcosan
• Target: Neuronal Signaling
• Solubility: Soluble to 100 mM in sterile water
• Storage: Store at RT
• IUPAC Name: 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;dihydrochloride
• InChI: InChI=1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
• InChIKey: FFNMBRCFFADNAO-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl

Pirenzepine Dihydrochloride(CAT: R004749) is a selective M1 muscarinic acetylcholine receptor antagonist with the molecular formula C₁₉H₂₁Cl₃N₄O. Clinically explored for its gastroprotective properties, it inhibits gastric acid secretion without significantly affecting other cholinergic systems. This compound has been studied for its therapeutic potential in treating peptic ulcers, functional dyspepsia, and even myopia progression. Pirenzepine Dihydrochloride is typically supplied as a white to off-white crystalline powder, soluble in water. Its high receptor selectivity makes it a valuable pharmacological tool in neuroscience and gastrointestinal research, where modulation of cholinergic signaling pathways is of interest.