Pirenoxine Sodium

• CAT Number: M015924
• CAS Number: 51410-30-1
• Molecular Formula: C16H7N2NaO5
• Molecular Weight: 330.231
• Purity: ≥95%
• Synonyms: PIRENOXINE SODIUM;1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALT;sodium 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylate;1-Hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylic acid sodium salt;Catalin sodium
• Storage: -20°C
• IUPAC Name: sodium;1,5-dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylate
• InChI: InChI=1S/C16H8N2O5.Na/c19-9-5-8(16(21)22)18-14-10(20)6-12-15(13(9)14)17-7-3-1-2-4-11(7)23-12;/h1-6H,(H,18,19)(H,21,22);/q;+1/p-1
• InChIKey: HDQXPMXHXZNPKE-UHFFFAOYSA-M
• SMILES: C1=CC=C2C(=C1)N=C3C(=CC(=O)C4=C3C(=O)C=C(N4)C(=O)[O-])O2.[Na+]

Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts. A report in the journal of Inorganic Chemistry showed that in liquid solutions pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye. Pirenoxine interacts with selenite or calcium ions that have been proven as factors leading to the formation of lens cataract.

Reference

1: Zhou Y, Hu Y, Zeng N, Ji Y, Dai X, Li P, Ma H, He Y. Noninvasive monitoring of
Pirenoxine Sodium concentration in aqueous humor based on dual-wavelength iris
imaging technique. Biomed Opt Express. 2011 Jan 5;2(2):231-42. doi:
10.1364/BOE.2.000231. PubMed PMID: 21339869; PubMed Central PMCID: PMC3038439.