Piperidin-4-one Ethylene Ketal

• CAT Number: R020328
• CAS Number: 177-11-7
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.19
• Purity: ≥95%
• Synonyms: 4,4-(Ethylenedioxy)piperidine; 4-Piperidinone Ethylene Acetal; 4-Piperidinone, Cyclic 1,2-Ethanediyl Acetal; 4-Piperidone Ethylene Acetal; 4-Piperidone Ethylene Ketal; 8-Aza-1,4-dioxaspiro[4.5]decane
• Storage: -20°C
• IUPAC Name: 1,4-dioxa-8-azaspiro[4.5]decane
• InChI: InChI=1S/C7H13NO2/c1-3-8-4-2-7(1)9-5-6-10-7/h8H,1-6H2
• InChIKey: KPKNTUUIEVXMOH-UHFFFAOYSA-N
• SMILES: C1CNCCC12OCCO2

Piperidin-4-one ethylene ketal (Cat No.: R020328) is a protected form of piperidin-4-one, where the ketone group is masked by forming a cyclic acetal (ketal) with ethylene glycol. This modification enhances the compound’s stability under basic or neutral conditions, preventing unwanted side reactions during multistep organic synthesis. It is commonly used as an intermediate in the preparation of pharmaceuticals, especially those involving piperidine-based scaffolds. The ketal group can be selectively removed under acidic conditions, allowing for controlled deprotection and further functional group transformations.