PIM1-IN-2

• CAT Number: R029067
• CAS Number: 477845-12-8
• Molecular Formula: C17H11ClN4O
• Molecular Weight: 322.75
• Purity: ≥95%
• Synonyms: 4-[3-(4-chlorophenyl)-2,1-benzoxazol-5-yl]pyrimidin-2-amine
• InChI: InChI=1S/C17H11ClN4O/c18-12-4-1-10(2-5-12)16-13-9-11(3-6-15(13)22-23-16)14-7-8-20-17(19)21-14/h1-9H,(H2,19,20,21)
• InChIKey: AQVFETGXIRKVAQ-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C2=C3C=C(C=CC3=NO2)C4=NC(=NC=C4)N)Cl

PIM1-IN-2（Cat No.:R029067）is a selective small-molecule inhibitor of PIM1 kinase, a serine/threonine kinase implicated in cell survival, proliferation, and oncogenesis. By blocking PIM1 activity, PIM1-IN-2 disrupts phosphorylation of downstream targets involved in cell cycle progression and anti-apoptotic signaling. It is widely used in cancer research to investigate the role of PIM1 in hematologic malignancies and solid tumors. PIM1-IN-2 aids in exploring kinase-driven oncogenic pathways and evaluating targeted therapeutic strategies. Its specificity makes it a valuable tool for studying PIM1’s biological functions and its potential as a drug target in oncology.