Picroside IV

For research use only. Not for therapeutic Use.

  • CAT Number: I044936
  • CAS Number: 211567-04-3
  • Molecular Formula: C24H28O12
  • Molecular Weight: 508.47
  • Purity: ≥95%
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Picroside IV(Cat No.:I044936)is an iridoid glycoside isolated from the medicinal plant Picrorhiza kurroa, a key herb in Ayurvedic medicine known for its hepatoprotective properties. Structurally, it consists of a cyclopentanoid monoterpene core linked to a glucose moiety, contributing to its solubility and bioactivity. Picroside IV exhibits antioxidant, anti-inflammatory, and liver-protective effects by scavenging free radicals and modulating cellular signaling pathways such as NF-κB. It is under investigation for treating liver disorders, including hepatitis and toxin-induced liver injury. This compound holds promise in natural therapeutic development and herbal formulation research.


CAS Number 211567-04-3
Synonyms

[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(1S,2S,4S,5S,6R,10S)-5-hydroxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-10-yl]oxy]oxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate

Molecular Formula C24H28O12
Purity ≥95%
IUPAC Name [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(1S,2S,4S,5S,6R,10S)-5-hydroxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-10-yl]oxy]oxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
InChI InChI=1S/C24H28O12/c25-10-24-16-13(17(28)21(24)36-24)7-8-32-22(16)35-23-20(31)19(30)18(29)14(34-23)9-33-15(27)6-3-11-1-4-12(26)5-2-11/h1-8,13-14,16-23,25-26,28-31H,9-10H2/b6-3+/t13-,14-,16-,17+,18-,19+,20-,21+,22+,23+,24-/m1/s1
InChIKey AKYYFSOMEOHPPO-LQQBYVAQSA-N
SMILES C1=CO[C@H]([C@H]2[C@@H]1[C@@H]([C@H]3[C@@]2(O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)COC(=O)/C=C/C5=CC=C(C=C5)O)O)O)O
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