Picropodophyllotoxin

  • CAT Number: I003667
  • CAS Number: 477-47-4
  • Molecular Formula: C₂₂H₂₂O₈
  • Molecular Weight: 414.41
  • Purity: ≥95%
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Picropodophyllotoxin (Cat.No:I003667) is a naturally occurring compound derived from the plant family Berberidaceae. It exhibits anticancer properties and has been studied for its potential in chemotherapy. Picropodophyllotoxin inhibits cell division by targeting microtubules and has shown activity against various cancer cell lines. Further research is ongoing to explore its therapeutic applications in cancer treatment.

Catalog Number I003667
CAS Number 477-47-4
Synonyms

(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

Molecular Formula

C₂₂H₂₂O₈

Purity 95%
Target IGF1R
Solubility in DMSO > 10 mM
Storage Store at -20°C
IC50 1 nM(IGF1R autophosphorylation)
IUPAC Name (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19+,20-/m0/s1
InChIKey YJGVMLPVUAXIQN-HAEOHBJNSA-N
SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

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