Picotamide - CAS 32828-81-2

Picotamide is an antiplatelet drug that inhibits both thromboxane A₂ (TXA₂) receptors (K_d = 325 nM) and TXA₂ synthase. It significantly inhibits basal and lipopolysaccharide-stimulated TXA₂ synthesis by rat peritoneal macrophages when used at 0.5 mM. Formulations containing picotamide have potential applications in the reduction of peripheral artery disease in patients with diabetes.

Catalog Number: R067013

CAS Number: 32828-81-2

PubChem Substance ID:355195359

Molecular Formula: C21H20N4O3

Molecular Weight:376.416

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

• Synonyms: 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide

Property

• Molecular Formula: C21H20N4O3
• Molecular Weight: 376.416
• Purity: ≥95%
• Storage: Room temperature

Computed Descriptor

• IUPAC Name: 4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide
• InChI: InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27)
• InChIKey: KYWCWBXGRWWINE-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)C(=O)NCC2=CN=CC=C2)C(=O)NCC3=CN=CC=C3