For research use only. Not for therapeutic Use.
PI3K-IN-30（Cat No.:I044076）is a potent and selective inhibitor of phosphoinositide 3-kinases (PI3Ks), key enzymes involved in the PI3K/AKT/mTOR signaling pathway, which regulates cell growth, survival, metabolism, and angiogenesis. By blocking PI3K activity, PI3K-IN-30 effectively suppresses oncogenic signaling, making it a valuable tool in cancer research, particularly for tumors driven by PIK3CA mutations or PTEN loss. This inhibitor is also useful in studying insulin signaling, inflammatory responses, and immune modulation. PI3K-IN-30 aids in the development of targeted therapies and in elucidating the role of PI3K in disease progression and drug resistance.
| CAS Number | 2281803-22-1 |
| Synonyms | 2-[[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]-(2-methoxyethyl)amino]ethanol |
| Molecular Formula | C20H25F2N7O3 |
| Purity | ≥95% |
| IUPAC Name | 2-[[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]-(2-methoxyethyl)amino]ethanol |
| InChI | InChI=1S/C20H25F2N7O3/c1-31-11-7-27(6-10-30)18-24-19(28-8-12-32-13-9-28)26-20(25-18)29-15-5-3-2-4-14(15)23-17(29)16(21)22/h2-5,16,30H,6-13H2,1H3 |
| InChIKey | DTTGBWQUOGWGMZ-UHFFFAOYSA-N |
| SMILES | COCCN(CCO)C1=NC(=NC(=N1)N2CCOCC2)N3C4=CC=CC=C4N=C3C(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
