PHPS1 sodium

• CAT Number: I014987
• CAS Number: 1177131-02-0
• Molecular Formula: C21H14N5NaO6S
• Molecular Weight: 487.42
• Purity: ≥95%
• Synonyms: sodium;4-[[5-(4-nitrophenyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]diazenyl]benzenesulfonate

PHPS1 sodium（Cat No.:I014987）is a selective small-molecule inhibitor of Src homology region 2 domain-containing phosphatase-2 (SHP2), a tyrosine phosphatase involved in cell signaling, growth, and survival. By blocking SHP2 activity, PHPS1 sodium interferes with downstream RAS/MAPK pathways, making it a valuable research tool in oncology, immunology, and developmental biology. It is commonly used to explore SHP2’s role in tumor progression, leukemia, and immune checkpoint regulation. The sodium salt form improves solubility and handling, supporting in vitro and in vivo studies for therapeutic discovery and mechanistic investigations.