Phosphoribosyl pyrophosphate pentasodium

• CAT Number: M008105
• CAS Number: 108321-05-7
• Molecular Formula: C5H8Na5O14P3
• Molecular Weight: 499.98
• Purity: ≥95%
• Synonyms: pentasodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[oxido(phosphonatooxy)phosphoryl]oxyoxolan-2-yl]methyl phosphate
• InChI: InChI=1S/C5H13O14P3.5Na/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13;;;;;/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13);;;;;/q;5*+1/p-5/t2-,3-,4-,5-;;;;;/m1...../s1
• InChIKey: UJNGSXHPBPBVKF-LVGJVSMDSA-I
• SMILES: C([C@@H]1[C@H]([C@H]([C@H](O1)OP(=O)([O-])OP(=O)([O-])[O-])O)O)OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+]

Phosphoribosyl pyrophosphate pentasodium (Cat No.:M008105) is a water-soluble nucleotide biosynthesis intermediate composed of a ribose sugar bound to a pyrophosphate group and five sodium counterions. PRPP plays a central role in the de novo and salvage pathways of purine and pyrimidine nucleotide synthesis. It serves as a key substrate for enzymes like phosphoribosyltransferases in the formation of nucleotides, NAD⁺, and histidine. The pentasodium form enhances stability and solubility for biochemical assays and cell-free systems. PRPP is widely used in metabolic studies, enzymology, and pharmaceutical research.