Phenformin hydrochloride

• CAT Number: A000869
• CAS Number: 834-28-6
• Molecular Formula: C₁₀H₁₅N₅ · HCl
• Molecular Weight: 241.72
• Purity: ≥95%
• Storage: -20°C
• InChI: InChI=1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
• InChIKey: YSUCWSWKRIOILX-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CCN=C(N)N=C(N)N.Cl

Phenformin Hydrochloride is the hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. It is potent to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus. Phenformin Hydrochloride improves insulin sensitivity and decrease insulin resistance by inhibiting complex 1 of the mitochondrial respiratory chain and inducing AMP-activated protein kinase (AMPK)-dependent signaling.

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