For research use only. Not for therapeutic Use.
PF-06273340（Cat No.:I008681）is a selective peptide inhibitor that targets the enzyme BTK (Bruton’s tyrosine kinase), a critical regulator in B-cell signaling and immune response. By inhibiting BTK, PF-06273340 effectively modulates B-cell activation, making it a promising candidate for research in autoimmune diseases, B-cell malignancies, and inflammatory conditions. Its high specificity and potency allow for precise exploration of BTK-related pathways, facilitating the development of targeted therapies for diseases like rheumatoid arthritis and certain cancers. PF-06273340 is a valuable tool for advancing therapeutic strategies in immunology and oncology.
| CAS Number | 1402438-74-7 |
| Synonyms | N-[5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-(5-chloropyridin-2-yl)acetamide |
| Molecular Formula | C23H22ClN7O3 |
| Purity | ≥95% |
| IUPAC Name | N-[5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-(5-chloropyridin-2-yl)acetamide |
| InChI | InChI=1S/C23H22ClN7O3/c1-23(2,12-32)31-11-18(17-10-28-22(25)30-21(17)31)20(34)13-5-16(9-26-7-13)29-19(33)6-15-4-3-14(24)8-27-15/h3-5,7-11,32H,6,12H2,1-2H3,(H,29,33)(H2,25,28,30) |
| InChIKey | BPIWZDNVMQQBQX-UHFFFAOYSA-N |
| SMILES | CC(C)(CO)N1C=C(C2=CN=C(N=C21)N)C(=O)C3=CC(=CN=C3)NC(=O)CC4=NC=C(C=C4)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
