For research use only. Not for therapeutic Use.
PF-03463275（Cat No.:I045839）is a potent and selective dopamine D1 receptor partial agonist developed for neuropsychiatric and cognitive disorder research. By modulating D1 receptor signaling, it enhances dopaminergic neurotransmission in the prefrontal cortex, a region critical for working memory, attention, and executive function. PF-03463275 has been investigated for potential therapeutic applications in schizophrenia, cognitive impairment, and other neurological conditions involving dopamine dysregulation. Researchers use this compound to study dopaminergic pathways, cognition-related signaling mechanisms, and therapeutic strategies targeting D1 receptors in psychiatric and neurodegenerative disease models.
| CAS Number | 1173239-39-8 |
| Synonyms | N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide |
| Molecular Formula | C19H22ClFN4O |
| Purity | ≥95% |
| IUPAC Name | N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide |
| InChI | InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15? |
| InChIKey | KYLOBHXXQOZRKK-YIONKMFJSA-N |
| SMILES | CN1C[C@@H]2[C@H](C1)C2CN(CC3=CC(=C(C=C3)F)Cl)C(=O)C4=CN(C=N4)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
