Perospirone hydrochloride

• CAT Number: M113405
• CAS Number: 129273-38-7
• Molecular Formula: C23H31ClN4O2S
• Molecular Weight: 463.04
• Purity: ≥95%
• Synonyms: (3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione;hydrochloride
• IUPAC Name: (3aS,7aR)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione;hydrochloride
• InChI: InChI=1S/C23H30N4O2S.ClH/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21;/h3-4,9-10,17-18H,1-2,5-8,11-16H2;1H/t17-,18+
• InChIKey: HIZFAPMOZFYELI-GNXQHMNLSA-N
• SMILES: C1CC[C@H]2[C@@H](C1)C(=O)N(C2=O)CCCCN3CCN(CC3)C4=NSC5=CC=CC=C54.Cl

Perospirone hydrochloride（Cat No.:M113405）is an atypical antipsychotic agent that acts as a serotonin 5-HT2A and dopamine D2 receptor antagonist, with additional partial agonist activity at 5-HT1A receptors. This receptor-binding profile contributes to its antipsychotic, anxiolytic, and mood-stabilizing properties. Clinically, perospirone hydrochloride has been studied for the treatment of schizophrenia and schizoaffective disorders, showing efficacy in reducing both positive and negative symptoms. Its pharmacological actions also support research into mood regulation and cognitive function. As a research tool, it is widely used to investigate serotonin–dopamine interactions in neuropsychiatric disease models.