For research use only. Not for therapeutic Use.
Periplocymarin(CAT: R072662) is a naturally occurring cardiac glycoside isolated from plants of the Periploca genus. Structurally related to digoxin-like compounds, it consists of a steroidal aglycone linked to a sugar moiety, enabling strong interactions with Na⁺/K⁺-ATPase. Through this mechanism, Periplocymarin exhibits potent cardiotonic activity, enhancing myocardial contractility. Beyond cardiovascular effects, it has demonstrated antitumor and pro-apoptotic properties in various cancer cell models, making it of growing interest in oncology research. As a bioactive natural product, Periplocymarin serves as a useful probe for studying cardiac pharmacology, cancer biology, and natural product drug discovery.
| CAS Number | 32476-67-8 |
| Synonyms | 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one |
| Molecular Formula | C30H46O8 |
| Purity | ≥95% |
| IUPAC Name | 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one |
| InChI | InChI=1S/C30H46O8/c1-17-26(32)23(35-4)14-25(37-17)38-19-5-9-27(2)21-6-10-28(3)20(18-13-24(31)36-16-18)8-12-30(28,34)22(21)7-11-29(27,33)15-19/h13,17,19-23,25-26,32-34H,5-12,14-16H2,1-4H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28-,29+,30+/m1/s1 |
| InChIKey | XRWQBDJPMXRDOQ-YUUDFPFBSA-N |
| SMILES | CC1C(C(CC(O1)OC2CCC3(C4CCC5(C(CCC5(C4CCC3(C2)O)O)C6=CC(=O)OC6)C)C)OC)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
