Perindopril Erbumine is a potent ACE inhibitor with IC50 of 1.05 nM.<br>Perindopril Erbumine displays a higher binding affinity for the bradykinin binding sites than the angiotensin I binding sites of the angiotensin-converting enzyme (ACE) with bradykinin/angiotensin I selectivity ratio of 1.44.<br>Oral administration of Perindopril Erbumine at 2 mg/kg/day has a significant inhibitory effect on SCC-VII tumor growth, and reduces blood vessel formation surrounding the tumors in vivo due to the suppression of VEGF-induced angiogenesis.
| Catalog Number | A000276 |
| CAS Number | 107133-36-8 |
| Synonyms | NA |
| Molecular Formula | C19H32N2O5.C4H11N |
| Purity | 95% |
| Target | RAAS |
| Solubility | Limited solubility |
| Storage | 3 years -20C powder |
