Perindopril Erbumine - CAS 107133-36-8
Perindopril Erbumine is a potent ACE inhibitor with IC50 of 1.05 nM.
Perindopril Erbumine displays a higher binding affinity for the bradykinin binding sites than the angiotensin I binding sites of the angiotensin-converting enzyme (ACE) with bradykinin/angiotensin I selectivity ratio of 1.44.
Oral administration of Perindopril Erbumine at 2 mg/kg/day has a significant inhibitory effect on SCC-VII tumor growth, and reduces blood vessel formation surrounding the tumors in vivo due to the suppression of VEGF-induced angiogenesis.
Catalog Number: A000276
CAS Number: 107133-36-8
PubChem Substance ID:355038925
Molecular Formula: C19H32N2O5.C4H11N
Molecular Weight:441.6
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
| Synonyms | NA |
|---|
Property
| Molecular Formula: | C19H32N2O5.C4H11N |
|---|---|
| Molecular Weight | 441.6 |
| Target: | RAAS |
| Solubility | Limited solubility |
| Purity | ≥95% |
| Storage | 3 years -20C powder |