Penicillin G benzathine

• CAT Number: M046439
• CAS Number: 1538-09-6
• Molecular Formula: C48H56N6O8S2
• Molecular Weight: 909.12
• Purity: ≥95%
• Synonyms: N,N’-dibenzylethane-1,2-diamine;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC Name: N,N'-dibenzylethane-1,2-diamine;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• InChI: InChI=1S/2C16H18N2O4S.C16H20N2/c2*1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h2*3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2/t2*11-,12+,14-;/m11./s1
• InChIKey: BVGLIYRKPOITBQ-ANPZCEIESA-N
• SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2

Penicillin G benzathine(CAT: M046439) is a long-acting β-lactam antibiotic formulation of benzathine and penicillin G. It exhibits potent bactericidal activity against Gram-positive organisms by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Due to its very low solubility, Penicillin G benzathine is slowly absorbed after intramuscular injection, providing prolonged serum concentrations. It is commonly used in research on antimicrobial resistance, bacterial infection models, and drug delivery studies. This compound is particularly relevant for studying streptococcal infections, syphilis, and rheumatic fever prophylaxis. Its extended-release profile makes it valuable for pharmacological investigations of long-acting antibiotic formulations.