For research use only. Not for therapeutic Use.
PDP-Pfp (Cat No.:I017809) is a heterobifunctional crosslinker designed for thiol-specific bioconjugation. It features a pyridyldithiol group that reacts with free sulfhydryls via disulfide exchange and a pentafluorophenyl (Pfp) ester that efficiently couples with primary amines, forming stable amide bonds. This dual reactivity allows PDP-Pfp to link proteins, peptides, and other biomolecules in a controlled manner. It is widely applied in antibody–drug conjugates, protein engineering, and biomaterial functionalization. PDP-Pfp provides versatility and stability, making it a valuable tool for advanced bioconjugation and chemical biology studies.
| CAS Number | 160580-70-1 |
| Synonyms | (2,3,4,5,6-pentafluorophenyl) 3-(pyridin-2-yldisulfanyl)propanoate |
| Molecular Formula | C14H8F5NO2S2 |
| Purity | ≥95% |
| IUPAC Name | (2,3,4,5,6-pentafluorophenyl) 3-(pyridin-2-yldisulfanyl)propanoate |
| InChI | InChI=1S/C14H8F5NO2S2/c15-9-10(16)12(18)14(13(19)11(9)17)22-8(21)4-6-23-24-7-3-1-2-5-20-7/h1-3,5H,4,6H2 |
| InChIKey | ICRMTRFPJXTUCG-UHFFFAOYSA-N |
| SMILES | C1=CC=NC(=C1)SSCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
