For research use only. Not for therapeutic Use.
PDD00017238（Cat No.:I034320）is a selective small-molecule inhibitor of USP7 (ubiquitin-specific protease 7), an enzyme that controls protein degradation through deubiquitination. By inhibiting USP7, PDD00017238 destabilizes oncogenic proteins and enhances p53 pathway activation, making it useful for studying cancer-related mechanisms and protein homeostasis. Researchers employ this compound to investigate the therapeutic potential of targeting ubiquitin signaling in oncology and immunology. With strong potency and selectivity, PDD00017238 serves as a chemical probe for understanding deubiquitination biology and advancing drug discovery efforts focused on the ubiquitin–proteasome regulatory network.
| CAS Number | 1952247-05-0 |
| Synonyms | 1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)benzimidazole-5-sulfonamide |
| Molecular Formula | C19H20N6O3S3 |
| Purity | ≥95% |
| IUPAC Name | 1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)benzimidazole-5-sulfonamide |
| InChI | InChI=1S/C19H20N6O3S3/c1-11-16(29-12(2)22-11)9-24-14-5-4-13(31(27,28)23-19(3)6-7-19)8-15(14)25(18(24)26)17-20-10-21-30-17/h4-5,8,10,23H,6-7,9H2,1-3H3 |
| InChIKey | FLUZEVGWXJVSPX-UHFFFAOYSA-N |
| SMILES | CC1=C(SC(=N1)C)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)N(C2=O)C5=NC=NS5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
