PCAF-IN-2

• CAT Number: I043499
• CAS Number: 56173-05-8
• Molecular Formula: C10H7F3N6
• Molecular Weight: 268.20
• Purity: ≥95%
• Synonyms: [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine
• InChI: InChI=1S/C10H7F3N6/c11-10(12,13)9-17-16-8-6-4-2-1-3-5(6)7(15-14)18-19(8)9/h1-4H,14H2,(H,15,18)
• InChIKey: VXUZXROYRSNHSD-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=NN3C2=NN=C3C(F)(F)F)NN

PCAF-IN-2（Cat No.:I043499）is a selective small-molecule inhibitor targeting the p300/CBP-associated factor (PCAF), a histone acetyltransferase involved in the regulation of gene expression and chromatin remodeling. PCAF plays a role in various cellular processes, including cell cycle regulation, apoptosis, and transcription. By inhibiting PCAF, PCAF-IN-2 modulates gene expression and can affect cellular pathways linked to cancer, inflammation, and other diseases. Research suggests that PCAF-IN-2 holds potential for therapeutic applications in oncology, particularly in cancers where altered gene expression and chromatin modifications contribute to tumorigenesis and resistance to treatments.