PC Alkyne-PEG4-NHS ester

• CAT Number: I016107
• CAS Number: 1802907-98-7
• Molecular Formula: C29H39N3O14
• Molecular Weight: 653.63
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 1-[5-methoxy-2-nitro-4-[4-oxo-4-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethylamino]butoxy]phenyl]ethyl carbonate
• InChI: InChI=1S/C29H39N3O14/c1-4-10-40-13-15-42-17-18-43-16-14-41-12-9-30-26(33)6-5-11-44-25-20-23(32(37)38)22(19-24(25)39-3)21(2)45-29(36)46-31-27(34)7-8-28(31)35/h1,19-21H,5-18H2,2-3H3,(H,30,33)
• InChIKey: AOWMPLACVFKCJJ-UHFFFAOYSA-N
• SMILES: CC(C1=CC(=C(C=C1[N+](=O)[O-])OCCCC(=O)NCCOCCOCCOCCOCC#C)OC)OC(=O)ON2C(=O)CCC2=O

PC Alkyne-PEG4-NHS ester（Cat No.:I016107）is a versatile heterobifunctional linker designed for bioconjugation, click chemistry, and targeted delivery applications. It contains an alkyne group for copper-catalyzed azide–alkyne cycloaddition (CuAAC) and an NHS ester that efficiently reacts with primary amines on proteins, peptides, or small molecules. The PEG4 spacer enhances water solubility, reduces steric hindrance, and provides flexibility for conjugation. This reagent enables stable, site-specific modification of biomolecules and polymers, making it highly valuable in antibody–drug conjugates, chemical biology research, and the development of diagnostic and therapeutic platforms.