PARP1-IN-8（Cat No.:I043670）is a potent inhibitor targeting PARP1 (Poly (ADP-ribose) polymerase 1), an enzyme involved in DNA repair processes. By inhibiting PARP1, PARP1-IN-8 disrupts the repair of DNA single-strand breaks, leading to the accumulation of DNA damage and inducing cell death, particularly in cancer cells with deficient DNA repair mechanisms. This makes it a promising candidate for treating cancers with BRCA mutations or defects in DNA repair. PARP1-IN-8 is being explored in cancer research, particularly in combination with other therapies to enhance tumor cell sensitivity to treatment.