For research use only. Not for therapeutic Use.
Paroxetine Hydrochloride (Cat No.:A000195) is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD). It works by increasing serotonin levels in the brain, helping regulate mood and emotional balance. Paroxetine is known for its strong affinity for the serotonin transporter and relatively short half-life. Available in tablet and oral suspension forms, it is effective but may cause side effects such as drowsiness, nausea, or withdrawal symptoms upon discontinuation.
CAS Number | 78246-49-8 |
Synonyms | 78246-49-8; Paroxetine Hcl; Paroxat; Aropax 20; (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride |
Molecular Formula | C19H21ClFNO3 |
Purity | ≥95% |
Target | Autophagy |
Solubility | Soluble in DMSO > 10 mM |
Storage | -20°C |
InChI | 1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1 |
InChIKey | GELRVIPPMNMYGS-RVXRQPKJSA-N |
SMILES | C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl |
Reference | 1: Brittain HG. Paroxetine hydrochloride: polymorphs and solvatomorphs. Profiles <br> 3: Khatavkar UN, Shimpi SL, Jayaram Kumar K, Deo KD. Development and comparative 4: Pae CU, Misra A, Ham BJ, Han C, Patkar AA, Masand PS. Paroxetine mesylate: 5: Jin SJ, Yoo YH, Kim MS, Kim JS, Park JS, Hwang SJ. Paroxetine hydrochloride 6: Venkatachalam A, Chatterjee VS. Stability-indicating high performance thin 7: Alarfaj N, Razeq SA, Sultan M. Spectrofluorimetric determination of paroxetine <br> 9: Roscoe JA, Morrow GR, Hickok JT, Mustian KM, Griggs JJ, Matteson SE, Bushunow 10: Erk N, Biryol I. Voltammetric and HPLC techniques for the determination of |
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