Parmodulin 2

• CAT Number: R059270
• CAS Number: 423735-93-7
• Molecular Formula: C17H17BrN2O2
• Molecular Weight: 361.23
• Purity: ≥95%
• Synonyms: 2-bromo-N-[3-(butanoylamino)phenyl]benzamide
• InChI: InChI=1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22)
• InChIKey: DFOVLSMXPWPCFH-UHFFFAOYSA-N
• SMILES: CCCC(=O)NC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2Br

Parmodulin 2（Cat No.:R059270）is a small-molecule modulator that selectively targets the protease-activated receptor 1 (PAR1), a key receptor in thrombin signaling. Unlike conventional PAR1 antagonists, it functions as a biased ligand, shifting signaling away from pathways that drive platelet aggregation and thrombosis while preserving protective endothelial responses. This unique mechanism positions Parmodulin 2 as a promising lead in antithrombotic therapy with reduced bleeding risk. In research, it is widely used to study vascular biology, coagulation pathways, and the development of safer cardiovascular therapeutics.