For research use only. Not for therapeutic Use.
p38 MAP Kinase Inhibitor VI (CAT: I040459) is a small-molecule inhibitor targeting the p38 mitogen-activated protein kinase (MAPK) pathway, a critical regulator of inflammation, cell differentiation, and stress response. With an inhibition rate of 24%, compound C32 serves as a moderately active probe for studying p38 MAPK-dependent signaling cascades in cellular and biochemical assays. It is useful for dissecting the role of p38 MAPK in various pathological conditions, including autoimmune disorders, neuroinflammation, and cancer. This compound supports early-stage pharmacological profiling and mechanistic studies aimed at validating p38 MAPK as a therapeutic target in inflammatory and stress-related disease models.
| CAS Number | 421578-46-3 |
| Synonyms | 2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1-(4-fluorophenyl)ethanone |
| Molecular Formula | C16H13FN2OS2 |
| Purity | ≥95% |
| IUPAC Name | 2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1-(4-fluorophenyl)ethanone |
| InChI | InChI=1S/C16H13FN2OS2/c1-9-10(2)22-16-14(9)15(18-8-19-16)21-7-13(20)11-3-5-12(17)6-4-11/h3-6,8H,7H2,1-2H3 |
| InChIKey | UGHHFQVLSOSMQA-UHFFFAOYSA-N |
| SMILES | CC1=C(SC2=C1C(=NC=N2)SCC(=O)C3=CC=C(C=C3)F)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
