p-Methoxybenzylmercaptan

• CAT Number: R003214
• CAS Number: 6258-60-2
• Molecular Formula: C8H10OS
• Molecular Weight: 154.23
• Purity: ≥95%
• Synonyms: 4-Methoxy-benzenemethanethiol; p-Methoxy-α-toluenethiol; (4-Methoxyphenyl)methanethiol; (4-Methoxyphenyl)methylthiol; p-Methoxybenzyl Mercaptan; p-Methoxybenzylthiol
• Storage: Desiccate at +4°C
• IUPAC Name: (4-methoxyphenyl)methanethiol
• InChI: InChI=1S/C8H10OS/c1-9-8-4-2-7(6-10)3-5-8/h2-5,10H,6H2,1H3
• InChIKey: PTDVPWWJRCOIIO-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)CS

p-Methoxybenzylmercaptan（Cat No.:R003214）, also known as 4-methoxybenzyl mercaptan, is an organosulfur compound featuring a methoxy-substituted benzene ring (at the para position) and a thiol (-SH) group attached via a methylene (-CH₂-) linker. This compound is commonly used as a protecting group for thiols and alcohols in organic synthesis due to the stability and ease of removal of the p-methoxybenzyl (PMB) group. Its thiol functionality also enables strong binding to metal surfaces, making it useful in surface modification and materials chemistry. It is employed in pharmaceuticals, bioconjugation, and peptide synthesis applications.