p-Iodobenzonitrile

• CAT Number: R070090
• CAS Number: 3058-39-7
• Molecular Formula: C7H4IN
• Molecular Weight: 229.02
• Purity: ≥95%
• Synonyms: 4-Iodobenzonitrile
• Storage: RT
• IUPAC Name: 4-iodobenzonitrile
• InChI: InChI=1S/C7H4IN/c8-7-3-1-6(5-9)2-4-7/h1-4H
• InChIKey: XOKDXPVXJWTSRM-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C#N)I

p-Iodobenzonitrile (CAT: R070090) is an aromatic halide featuring an iodine atom at the para-position relative to a nitrile group on the benzene ring. This compound serves as a valuable synthetic intermediate in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki, Sonogashira, and Heck reactions. The nitrile group offers an electron-withdrawing effect, enhancing reactivity and enabling further functionalization toward amides, tetrazoles, and heterocycles. p-Iodobenzonitrile is widely used in pharmaceutical development, materials science, and fine chemical production, where its para-substitution pattern supports regioselective transformations and structure–activity relationship (SAR) studies.