Orientin

• CAT Number: R039874
• CAS Number: 28608-75-5
• Molecular Formula: C21H20O11
• Molecular Weight: 448.38
• Purity: ≥95%
• Synonyms: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
• InChI: InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1
• InChIKey: PLAPMLGJVGLZOV-VPRICQMDSA-N
• SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O

Orientin(CAT: R039874) (luteolin-8-C-glucoside) is a naturally occurring flavonoid C-glycoside widely distributed in medicinal plants such as Ocimum sanctum (holy basil) and Passiflora species. It demonstrates diverse pharmacological activities, including antioxidant, anti-inflammatory, cardioprotective, neuroprotective, and anticancer effects. Research indicates that Orientin can scavenge free radicals, modulate NF-κB and MAPK signaling pathways, and protect against oxidative stress–induced cellular damage. It has also shown promise in improving myocardial function, enhancing cognitive performance, and supporting vascular health. With its broad therapeutic potential, Orientin serves as an important reference compound for natural product research, phytochemistry, and drug discovery focused on metabolic, neurological, and cardiovascular disorders.