Olanzapine

• CAT Number: A000340
• CAS Number: 132539-06-1
• Molecular Formula: C17H20N4S
• Molecular Weight: 312.4
• Purity: ≥95%
• Synonyms: 132539-06-1; Zyprexa; Zyprexa Zydis; Olansek; Zalasta
• Target: 5-HT Receptor
• Solubility: >15.6mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
• InChIKey: WXPNDRBBWZMPQG-UHFFFAOYSA-N
• SMILES: CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C

Olanzapine(cas 132539-06-1) is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quetiapine. It is a dopamine antagonist and is classified as a thienobenzodiazepine.

Reference

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2: Fulton B, Goa KL. Olanzapine. A review of its pharmacological properties and
therapeutic efficacy in the management of schizophrenia and related psychoses.
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3: Littrell K, Peabody CD, Littrell SH. Olanzapine: a new atypical antipsychotic.
J Psychosoc Nurs Ment Health Serv. 1996 Aug;34(8):41-6. Review. PubMed PMID:
8856604.

4: Meltzer HY, Fibiger HC. Olanzapine: a new typical antipsychotic drug.
Neuropsychopharmacology. 1996 Feb;14(2):83-5. Review. PubMed PMID: 8822530.