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Olanzapine

Olanzapine

  • CAT Number: A000340
  • CAS Number: 132539-06-1
  • Molecular Formula: C17H20N4S
  • Molecular Weight: 312.4
  • Purity: ≥95%
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Olanzapine(cas 132539-06-1) is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quetiapine. It is a dopamine antagonist and is classified as a thienobenzodiazepine.

Catalog Number A000340
CAS Number 132539-06-1
Molecular Formula

C17H20N4S

Purity 95%
Target 5-HT Receptor
Solubility >15.6mg/mL in DMSO
Storage -20°C
InChI 1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
InChIKey WXPNDRBBWZMPQG-UHFFFAOYSA-N
SMILES CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
Reference

1: Bever KA, Perry PJ. Olanzapine: a serotonin-dopamine-receptor antagonist for
antipsychotic therapy. Am J Health Syst Pharm. 1998 May 15;55(10):1003-16.
Review. PubMed PMID: 9606451.
<br>

2: Fulton B, Goa KL. Olanzapine. A review of its pharmacological properties and
therapeutic efficacy in the management of schizophrenia and related psychoses.
Drugs. 1997 Feb;53(2):281-98. Review. PubMed PMID: 9028746.
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3: Littrell K, Peabody CD, Littrell SH. Olanzapine: a new atypical antipsychotic.
J Psychosoc Nurs Ment Health Serv. 1996 Aug;34(8):41-6. Review. PubMed PMID:
8856604.
<br>

4: Meltzer HY, Fibiger HC. Olanzapine: a new typical antipsychotic drug.
Neuropsychopharmacology. 1996 Feb;14(2):83-5. Review. PubMed PMID: 8822530.

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