For research use only. Not for therapeutic Use.
ODN INH-18 sodium(CAT: I040298) is a synthetic 24-mer inhibitory oligodeoxynucleotide (INH-ODN) of class B, composed of the 5′ INH-ODN 4084-F sequence followed by a 12-nucleotide random sequence specifically designed to minimize secondary structure formation. This linear design enhances its stability and accessibility for target binding. ODN INH-18 functions as a potent antagonist of Toll-like receptor 9 (TLR9), effectively suppressing TLR9 ligand-induced interferon-α (IFN-α) production. It is a valuable tool for investigating innate immune modulation, particularly in autoimmune disease models, inflammation research, and TLR9 pathway studies.
| Purity | ≥95% |
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