Octyl glucose neopentyl glycol

• CAT Number: I044646
• CAS Number: 1257853-32-9
• Molecular Formula: C27H52O12
• Molecular Weight: 568.69
• Purity: ≥95%
• Synonyms: (2R,3R,4S,5S,6R)-2-[2-hexyl-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]octoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• IUPAC Name: (2S,3S,4R,5R,6S)-2-[2-hexyl-2-[[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]octoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C27H52O12/c1-3-5-7-9-11-27(12-10-8-6-4-2,15-36-25-23(34)21(32)19(30)17(13-28)38-25)16-37-26-24(35)22(33)20(31)18(14-29)39-26/h17-26,28-35H,3-16H2,1-2H3/t17-,18-,19-,20-,21+,22+,23-,24-,25-,26-/m0/s1
• InChIKey: TYXCLOLHZMMLEK-RNDJEAJNSA-N
• SMILES: CCCCCCC(CCCCCC)(CO[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)CO)O)O)O)CO[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)CO)O)O)O

Octyl Glucose Neopentyl Glycol (Cat No.:I044646) is a non-ionic, amphiphilic detergent used for the extraction, solubilization, and stabilization of membrane proteins. It features a neopentyl glycol core connected to two octyl (C8) alkyl chains and two glucose head groups, offering a balanced hydrophilic-lipophilic structure. OGNG has a low critical micelle concentration and mild detergent properties, preserving the native structure and function of delicate proteins such as G protein–coupled receptors (GPCRs), transporters, and enzymes. It is particularly valuable in structural studies, including X-ray crystallography and cryo-EM, due to its ability to maintain protein integrity.