Obtustatin triacetate

• CAT Number: I040247
• Molecular Formula: C184H284N52O57S8.3C2H4O2
• Molecular Weight: 4573.21
• Purity: ≥95%

Obtustatin triacetate(CAT: I040247) is a 41-amino acid non-RGD disintegrin derived from the venom of Vipera lebetina obtusa. This peptide is a potent and selective inhibitor of integrin α1β1, blocking its adhesion to type IV collagen. By interfering with integrin-mediated cell–matrix interactions, Obtustatin triacetate effectively inhibits angiogenesis, making it a valuable tool in cancer research and studies of tumor vascularization. Its specificity and mechanism of action make it suitable for probing integrin α1β1 signaling pathways, anti-angiogenic drug development, and the modulation of extracellular matrix interactions in pathological conditions such as cancer and fibrosis.