For research use only. Not for therapeutic Use.
OATD-01（Cat No.:I033763）is a potent, selective inhibitor of chitotriosidase-1 (CHIT1), an enzyme implicated in inflammatory and fibrotic processes. Designed to target macrophage-driven pathologies, OATD-01 has demonstrated strong anti-inflammatory and anti-fibrotic activity in preclinical models of idiopathic pulmonary fibrosis (IPF) and sarcoidosis. By modulating macrophage activation and reducing pro-fibrotic cytokine production, OATD-01 offers a novel therapeutic approach for chronic respiratory and inflammatory diseases. Its oral bioavailability and targeted mechanism make it a promising candidate for clinical development in treating macrophage-mediated pathologies.
| CAS Number | 2088453-21-6 |
| Synonyms | 3-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methylmorpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine |
| Molecular Formula | C19H27ClN6O |
| Purity | ≥95% |
| IUPAC Name | 3-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methylmorpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine |
| InChI | InChI=1S/C19H27ClN6O/c1-13-11-26(17(12-27-13)10-14-2-4-15(20)5-3-14)16-6-8-25(9-7-16)19-22-18(21)23-24-19/h2-5,13,16-17H,6-12H2,1H3,(H3,21,22,23,24)/t13-,17-/m0/s1 |
| InChIKey | STWVLEKJQQRGMO-GUYCJALGSA-N |
| SMILES | C[C@H]1CN([C@H](CO1)CC2=CC=C(C=C2)Cl)C3CCN(CC3)C4=NNC(=N4)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
