O-Desaryl Ranolazine-d5

• CAT Number: R014268
• CAS Number: NA
• Molecular Formula: C₁₇H₂₂D₅N₃O₃
• Molecular Weight: 326.45
• Purity: ≥95%
• Synonyms: 4-(2,3-Dihydroxypropyl)-N-(2,6-dimethylphenyl)-1-piperazineacetamide-d5; RS 88640-d5; CVT-2512-d5
• Storage: -20°C
• IUPAC Name: N-(2,6-dimethylphenyl)-2-[4-(1,1,2,3,3-pentadeuterio-2,3-dihydroxypropyl)piperazin-1-yl]acetamide
• InChI: InChI=1S/C17H27N3O3/c1-13-4-3-5-14(2)17(13)18-16(23)11-20-8-6-19(7-9-20)10-15(22)12-21/h3-5,15,21-22H,6-12H2,1-2H3,(H,18,23)/i10D2,12D2,15D
• InChIKey: LDEJNELBMSFPDJ-WBPADLBPSA-N
• SMILES: [2H]C([2H])(C([2H])(C([2H])([2H])O)O)N1CCN(CC1)CC(=O)NC2=C(C=CC=C2C)C

O-Desaryl Ranolazine-d5 is a deuterated form of O-desaryl ranolazine, a metabolite of ranolazine, a drug used to treat chronic angina. This compound features five deuterium atoms, which enhance its stability and allow for precise tracking in pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. O-Desaryl Ranolazine-d5 is particularly valuable in investigating the metabolic pathways of ranolazine, specifically focusing on the formation and activity of its metabolites. It serves as a reliable internal standard in analytical chemistry, ensuring accurate and reproducible results in the study of cardiovascular therapies, especially in understanding the pharmacokinetics and efficacy of ranolazine and its related compounds.