NSI-189 - CAS 1270138-40-3

NSI-189 (CAT:I008377) is a niacinamide piperazine derivative. It can stimulate the neurogenesis of human hippocampal neural stem cells, so it is promising for major depression, Alzheimer’s disease, center and other brain diseases. This product is used for organic synthesis, drug development, and other scientific research purposes.

Catalog Number: I008377

CAS Number: 1270138-40-3

PubChem Substance ID:348355161

Molecular Formula: C22H30N4O

Molecular Weight:366.4998

Purity: ≥95%

* For research use only. Not for human or veterinary use.




Molecular Formula: C22H30N4O
Molecular Weight366.4998
SolubilitySoluble in DMSO, not in water
Storage0 - 4 °C for short term, or -20 °C for long term
Overview of Clinical ResearchOriginator Neuralstem <br>Developer Palisade Bio; University of California, San Diego <br>Class Antidepressants; Antihyperglycaemics; Neuroprotectants; Nootropics; Piperazines; Pyridines; Small molecules; Vascular disorder therapies <br>Mechanism of Action Neurogenesis stimulants <br>Orphan Drug StatusYes – Angelman syndrome <br>New Molecular Entity Yes <br>Available For Licensing Yes

Computed Descriptor

IUPAC Name(4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone