NOTA (Cat No.:I045300) is a triazamacrocyclic chelating agent widely used in radiochemistry and molecular imaging. Its three acetic acid arms and nitrogen-rich macrocyclic ring enable strong, stable complexation with radiometals such as gallium-68, copper-64, and indium-111. NOTA’s high thermodynamic stability and kinetic inertness make it ideal for developing radiolabeled biomolecules, including peptides, antibodies, and small molecules, for positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Its compact structure offers rapid complexation under mild conditions, supporting sensitive, targeted imaging in cancer diagnosis, cardiovascular research, and other biomedical applications.