NOTA-FAPI-4 - CAS 2374782-03-1

NOTA-FAPI-4(Cat No.:I033480), an analog of FAPI-4, is a potent inhibitor of fibroblast activation protein (FAP). It finds utility in the diagnosis and treatment of diseases characterized by the overexpression of FAP. As a PET tracer, NOTA-FAPI-4 enables the detection of diseases or disorders associated with FAP. This includes various types of cancers where FAP is upregulated. By specifically targeting FAP, NOTA-FAPI-4 allows for non-invasive imaging and facilitates the identification and monitoring of FAP-related conditions for improved diagnosis and personalized treatment strategies.

Catalog Number: I033480

CAS Number: 2374782-03-1

Molecular Formula: C36H47F2N9O8

Molecular Weight:771.82

Purity: 98.0%

Appearance:Solid powder

* For research use only. Not for human or veterinary use.

Synonym

SynonymsNOTA-FAPI-4;

Property

Molecular Formula: C36H47F2N9O8
Molecular Weight771.82
SolubilityTo be determined
Purity98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Computed Descriptor

IUPAC Name(S)-2,2'-(7-(2-(4-(3-((4-((2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7-triazonane-1,4-diyl)diacetic acid
InChIInChI=1S/C36H47F2N9O8/c37-36(38)19-26(20-39)47(25-36)31(48)21-41-35(54)28-4-5-40-30-3-2-27(18-29(28)30)55-17-1-6-42-13-15-46(16-14-42)32(49)22-43-7-9-44(23-33(50)51)11-12-45(10-8-43)24-34(52)53/h2-5,18,26H,1,6-17,19,21-25H2,(H,41,54)(H,50,51)(H,52,53)/t26-/m0/s1
InChIKeyXQARGGQZFNOLDH-SANMLTNESA-N
SMILESO=C(C1=CC=NC2=CC=C(C=C21)OCCCN3CCN(CC3)C(CN4CCN(CCN(CC4)CC(O)=O)CC(O)=O)=O)NCC(N5CC(F)(C[C@@]5([H])C#N)F)=O