NODAGA-tris(t-Bu ester)

• CAT Number: I040645
• CAS Number: 1190101-34-8
• Molecular Formula: C27H49N3O8
• Molecular Weight: 543.69
• Purity: ≥95%
• Synonyms: 4-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
• InChI: InChI=1S/C27H49N3O8/c1-25(2,3)36-22(33)18-28-12-13-29(19-23(34)37-26(4,5)6)15-17-30(16-14-28)20(10-11-21(31)32)24(35)38-27(7,8)9/h20H,10-19H2,1-9H3,(H,31,32)
• InChIKey: ADHGPCATMVZKLP-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CN1CCN(CCN(CC1)C(CCC(=O)O)C(=O)OC(C)(C)C)CC(=O)OC(C)(C)C

NODAGA-tris(t-Bu ester) (NODAG)(CAT: I040645) is a protected derivative of the chelating agent NODAGA, widely used in the development of radiolabeled biomolecules for positron emission tomography (PET) imaging. The tert-butyl ester-protected form enhances solubility and stability during peptide synthesis and conjugation procedures. NODAG is designed for efficient coupling to peptides, antibodies, and other biomolecules, enabling subsequent radiometal chelation (e.g., ^68Ga, ^64Cu) for high-resolution molecular imaging. Its versatility and strong chelating ability make it an ideal tool for researchers developing targeted imaging agents in oncology, cardiology, and inflammatory disease diagnostics.