N,N,O-Tridesmethylvenlafaxine

• CAT Number: R044919
• CAS Number: 149289-29-2
• Molecular Formula: C14H21NO2
• Molecular Weight: 235.32
• Purity: ≥95%
• Synonyms: 4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol
• InChI: InChI=1S/C14H21NO2/c15-10-13(11-4-6-12(16)7-5-11)14(17)8-2-1-3-9-14/h4-7,13,16-17H,1-3,8-10,15H2
• InChIKey: BHCUWXACHAFFSK-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)(C(CN)C2=CC=C(C=C2)O)O

N,N,O-Tridesmethylvenlafaxine（Cat No.:R044919）is an active metabolite of venlafaxine, a serotonin–norepinephrine reuptake inhibitor (SNRI) widely used as an antidepressant. This compound retains pharmacological activity by modulating monoamine neurotransmitter levels, thereby influencing mood regulation and stress response. It is primarily used in pharmacokinetic and metabolism studies to investigate venlafaxine biotransformation, metabolic pathways, and interindividual variability in drug response. Researchers employ N,N,O-Tridesmethylvenlafaxine to study therapeutic mechanisms, antidepressant efficacy, and drug–drug interactions. Its role as a metabolite makes it valuable in neuropharmacology, psychiatric research, and personalized medicine studies.