For research use only. Not for therapeutic Use.
NNC-711 hydrochloride（Cat No.:R014382）is a potent and selective inhibitor of the GABA transporter subtype 1 (GAT-1), which is responsible for the reuptake of gamma-aminobutyric acid (GABA) from the synaptic cleft. By blocking GAT-1, NNC-711 increases extracellular GABA levels, enhancing inhibitory neurotransmission in the central nervous system. It is widely used in neuroscience research to study GABAergic signaling, epilepsy, anxiety, and other neurological disorders. NNC-711 hydrochloride serves as a valuable pharmacological tool for exploring GABA transport dynamics and for developing therapeutic strategies targeting GABA reuptake in CNS diseases.
| CAS Number | 145645-62-1 |
| Synonyms | 1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;hydrochloride |
| Molecular Formula | C21H23ClN2O3 |
| Purity | ≥95% |
| IUPAC Name | 1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;hydrochloride |
| InChI | InChI=1S/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18;/h1-6,8-12H,7,13-16H2,(H,24,25);1H |
| InChIKey | YZYRTEYMUTWJPL-UHFFFAOYSA-N |
| SMILES | C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
