N,N’-Diisopropylcarbodiimide

• CAT Number: R014241
• CAS Number: 693-13-0
• Molecular Formula: C7H14N2
• Molecular Weight: 126.20
• Purity: ≥95%
• Synonyms: N,N’-Methanetetraylbis-2-propanamine; 1,3-Diisopropylcarbodiimide; DIC; DIPC; DIPCDI; Diisopropylcarbodiimide; NSC 42080
• Storage: -20°C
• IUPAC Name: N,N’-Diisopropylcarbodiimide
• InChI: InChI=1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
• InChIKey: BDNKZNFMNDZQMI-UHFFFAOYSA-N
• SMILES: CC(C)N=C=NC(C)C

N,N’-Diisopropylcarbodiimide (CAT: R014241) is a highly efficient coupling reagent widely used in peptide synthesis and other condensation reactions. As a sterically hindered carbodiimide, it promotes amide and ester bond formation with minimal side reactions, making it ideal for solid-phase and solution-phase synthesis. DIC is favored for its solubility in organic solvents and compatibility with a broad range of functional groups. It is often paired with additives like HOBt or Oxyma to enhance coupling efficiency and reduce racemization. With broad applications in medicinal chemistry and material science, DIC is a key reagent for constructing complex molecular architectures.