N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid monohydrochloride hydrate - CAS 35369-53-0

N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid monohydrochloride hydrate (CAS 35369-53-0), also known as HBED, is an iron chelator and hydroxyl radical inhibitor.HBED is described to facilitate Fe(II) oxidation and to block O2(.-)-induced reduction of Fe(III), consequently blocking the Fe-mediated formation of hydroxyl radicals. HBED has been utilized as a tool for studying the involvement of hydroxyl radicals in cellular processes. HBED has specifically demonstrated to inhibit H2O2-induced apoptosis in neutrophils, suggesting participation of hydroxyl radicals in the mediation of neutrophilic apoptosis.

Catalog Number: M144091

CAS Number: 35369-53-0

Molecular Formula: C20H24N2O6·HCl·XH2O

Molecular Weight:424.89

Purity: ≥95%

Appearance:off-white powder

* For research use only. Not for human or veterinary use.

Synonym

SynonymsHBED

Property

Molecular Formula: C20H24N2O6·HCl·XH2O
Molecular Weight424.89
Purity≥95%
StorageStore at 0-8°C

Computed Descriptor

IUPAC Name2-[2-[carboxymethyl-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetic acid
InChIInChI=1S/C20H24N2O6/c23-17-7-3-1-5-15(17)11-21(13-19(25)26)9-10-22(14-20(27)28)12-16-6-2-4-8-18(16)24/h1-8,23-24H,9-14H2,(H,25,26)(H,27,28)
InChIKeyGRUVVLWKPGIYEG-UHFFFAOYSA-N
SMILESC1=CC=C(C(=C1)CN(CCN(CC2=CC=CC=C2O)CC(=O)O)CC(=O)O)O