N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid monohydrochloride hydrate - CAS 35369-53-0
N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid monohydrochloride hydrate (CAS 35369-53-0), also known as HBED, is an iron chelator and hydroxyl radical inhibitor.HBED is described to facilitate Fe(II) oxidation and to block O2(.-)-induced reduction of Fe(III), consequently blocking the Fe-mediated formation of hydroxyl radicals. HBED has been utilized as a tool for studying the involvement of hydroxyl radicals in cellular processes. HBED has specifically demonstrated to inhibit H2O2-induced apoptosis in neutrophils, suggesting participation of hydroxyl radicals in the mediation of neutrophilic apoptosis.
* For research use only. Not for human or veterinary use.
|Storage||Store at 0-8°C|
|IUPAC Name||2-[2-[carboxymethyl-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetic acid|