For research use only. Not for therapeutic Use.
(±)-Nipecotic acid（Cat No.:R050725）is a racemic mixture of the D- and L-enantiomers of nipecotic acid, a saturated heterocyclic amino acid featuring a piperidine ring with a carboxylic acid group at the 2-position. It acts as a potent inhibitor of GABA (gamma-aminobutyric acid) reuptake by blocking GABA transporters (GATs), thereby increasing extracellular GABA levels and enhancing inhibitory neurotransmission. Widely used in neuroscience research, (±)-nipecotic acid helps investigate GABAergic signaling and serves as a pharmacological tool in epilepsy and anxiety studies. Its structural simplicity and biological relevance make it valuable in neuropharmacology.
| CAS Number | 498-95-3 |
| Synonyms | 3-Piperidinecarboxylic Acid; Nipecotic Acid; (+/-)-β-Homoproline; 3-Carboxypiperidine; DL-Nipecotic Acid; Hexahydronicotinic Acid; |
| Molecular Formula | C6H11NO2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | 4°C |
| IUPAC Name | piperidine-3-carboxylic acid |
| InChI | InChI=1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9) |
| InChIKey | XJLSEXAGTJCILF-UHFFFAOYSA-N |
| SMILES | C1CC(CNC1)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
