Nicorandil-d4（Cat No.:R006897）is a deuterium-labeled analog of nicorandil, a vasodilatory drug used primarily in the treatment of angina pectoris. It contains four deuterium atoms, enabling precise tracking and quantification in pharmacokinetic and metabolic studies using mass spectrometry. Nicorandil-d4 retains the dual mechanism of the parent compound, acting as both a nitrate donor and ATP-sensitive potassium (K⁺<sub>ATP</sub>) channel opener. This dual action promotes coronary and peripheral vasodilation, reducing cardiac workload. Nicorandil-d4 is essential in drug metabolism research, providing accurate data on absorption, distribution, and clearance without altering the therapeutic properties of the original molecule.