NH-bis(PEG2-C2-Boc)

• CAT Number: I014519
• CAS Number: 1964503-36-3
• Molecular Formula: C22H43NO8
• Molecular Weight: 449.58
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethylamino]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C22H43NO8/c1-21(2,3)30-19(24)7-11-26-15-17-28-13-9-23-10-14-29-18-16-27-12-8-20(25)31-22(4,5)6/h23H,7-18H2,1-6H3
• InChIKey: AFSYLABPPWEICE-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCNCCOCCOCCC(=O)OC(C)(C)C

NH-bis(PEG2-C2-Boc)（Cat No.:I014519）is a bifunctional PEG-based linker featuring a central amine core connected to two PEG2-C2 arms, each terminated with a Boc-protected amine. The Boc groups act as protective units, removable under mild acidic conditions to release free primary amines for further conjugation with carboxylic acids, activated esters, or isocyanates. The PEG2-C2 spacers improve hydrophilicity, impart flexibility, and minimize steric hindrance, facilitating efficient bioconjugation. This reagent is highly valuable for drug conjugate synthesis, polymer modification, biomaterials engineering, and chemical biology applications requiring symmetrical multivalent amine functionalization.