NGB 2904（Cat No.:M032909）is a highly selective and potent dopamine D3 receptor antagonist with minimal affinity for D2 receptors. It is widely used in neuropharmacological research to investigate the role of D3 receptors in reward, addiction, and psychiatric disorders. By blocking D3 receptor signaling, NGB 2904 reduces drug-seeking behavior in preclinical models of substance abuse, particularly cocaine and nicotine. Its selectivity makes it a valuable tool for differentiating D3-specific pathways from broader dopaminergic mechanisms. NGB 2904 supports the development of targeted therapies for addiction and neuropsychiatric conditions involving D3 receptor dysregulation.