NFAT Inhibitor-2

For research use only. Not for therapeutic Use.

  • CAT Number: I043947
  • CAS Number: 422546-87-0
  • Molecular Formula: C22H20F2N2O4S
  • Molecular Weight: 446.47
  • Purity: ≥95%
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NFAT Inhibitor-2(Cat No.:I043947)is a selective small-molecule inhibitor targeting the nuclear factor of activated T-cells (NFAT) signaling pathway, which plays a central role in immune cell activation, differentiation, and cytokine production. By blocking NFAT translocation and transcriptional activity, NFAT Inhibitor-2 suppresses T-cell-mediated immune responses, making it valuable for studying autoimmune disorders, inflammation, and transplant rejection. Researchers use this compound to dissect NFAT-dependent gene expression and identify potential therapeutic targets. Its specificity and effectiveness support its application in developing immunomodulatory therapies for diseases driven by aberrant NFAT signaling.


CAS Number 422546-87-0
Synonyms

4-fluoro-N-(3-fluoro-4-methylphenyl)-3-[(4-methoxyphenyl)methylsulfamoyl]benzamide

Molecular Formula C22H20F2N2O4S
Purity ≥95%
IUPAC Name 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-[(4-methoxyphenyl)methylsulfamoyl]benzamide
InChI InChI=1S/C22H20F2N2O4S/c1-14-3-7-17(12-20(14)24)26-22(27)16-6-10-19(23)21(11-16)31(28,29)25-13-15-4-8-18(30-2)9-5-15/h3-12,25H,13H2,1-2H3,(H,26,27)
InChIKey UILNVCFXMNSVLA-UHFFFAOYSA-N
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)F)S(=O)(=O)NCC3=CC=C(C=C3)OC)F
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