NF023 hexasodium

• CAT Number: M002436
• CAS Number: 104869-31-0
• Molecular Formula: C35H20N4Na6O21S6
• Molecular Weight: 1162.88
• Purity: ≥95%
• Synonyms: hexasodium;8-[[3-[[3-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
• InChI: InChI=1S/C35H26N4O21S6.6Na/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);;;;;;/q;6*+1/p-6
• InChIKey: FMQURVHYTBGYSQ-UHFFFAOYSA-H
• SMILES: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C4C(=CC(=CC4=C(C=C3)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC5=C6C(=CC(=CC6=C(C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

NF023 hexasodium（Cat No.:M002436）is a selective antagonist of the P2X receptor family, particularly P2X1 and P2X2/3 subtypes, which are ATP-gated ion channels involved in neurotransmission, inflammation, and pain signaling. By blocking receptor activation, NF023 modulates purinergic signaling pathways, reducing excitatory responses linked to inflammatory and neuropathic conditions. Supplied as a hexasodium salt, it offers excellent solubility for experimental applications. NF023 is widely used in pharmacological research to dissect purinergic receptor function, investigate ATP-mediated signaling, and explore therapeutic strategies for inflammation, pain, and neurological disorders.