For research use only. Not for therapeutic Use.
Netropsin dihydrochloride(Cat No.:M084937)is a synthetic antibiotic and DNA-binding agent belonging to the oligopeptide family. It binds preferentially to AT-rich regions of the minor groove of DNA, interfering with replication and transcription processes. Originally isolated from Streptomyces species, Netropsin and its salts have been widely studied as molecular probes in nucleic acid research. Netropsin dihydrochloride is particularly valuable for studying DNA–protein interactions, sequence recognition, and gene regulation. Its strong affinity for DNA and defined binding specificity make it a powerful tool in biochemical and pharmacological investigations.
CAS Number | 18133-22-7 |
Synonyms | N-[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]-4-[[2-(diaminomethylideneamino)acetyl]amino]-1-methylpyrrole-2-carboxamide;dihydrochloride |
Molecular Formula | C18H28Cl2N10O3 |
Purity | ≥95% |
IUPAC Name | N-[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]-4-[[2-(diaminomethylideneamino)acetyl]amino]-1-methylpyrrole-2-carboxamide;dihydrochloride |
InChI | InChI=1S/C18H26N10O3.2ClH/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22;;/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24);2*1H |
InChIKey | SDRHUASONSRLFR-UHFFFAOYSA-N |
SMILES | CN1C=C(C=C1C(=O)NC2=CN(C(=C2)C(=O)NCCC(=N)N)C)NC(=O)CN=C(N)N.Cl.Cl |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |